Hate to say it, but Marie Rose and Honoka are SUPER popular in Japan, heck even Kasumi was pushed back when promoting DOAX3 and DOAX3 venus.
they will 100% be back in DOA6.
I just can't imagine the close up hit in the face for both of them... Also the bruises n' all. They're popular in Japan but not sure if they like seeing them getting hit & wounded at a more brutal level than DoA5. So I thought they might not enter DoA6 but they'll be there in the extreme series.