Yeah it is. I don't wanna brag but I'm kind of a pro at Skyrim. I always like trying out different character builds and stuff. I have mad amounts of characters in that game haha.
Everything is or will be OP in Skyrim except for lockpicking, lol. Best racial abilities are Argonian and Orc. While Nord, Breton and Dark Elf have the best resisrances.
I think that the Khaijit will be best for new players because they start out with better sneak and stamina. Even speech too (but come on, no one really cares about speech in Skyrim lol). But yea, I love the nightingalr armor. Its the most badass.
I believe nightingale armor is the best after level 46. The enchantments become stronger when your level is higher. I believe there are 4 versions of it.
Also the disease is a very small problem. You can always touch a shrine or use a cure disease potion.
Not to mention the stats at the start are really easy to get anyways. For the most skills at least.
What kind of player are you? Im more of the sneaky archer type. I made my sneak and archery legendary a long time ago. And close range fighting, I either use 2 daedric daggers (one does shock damge and the other does fire damage) or use the nightingale blade with chillrend or dawnbreaker. And if I need a shield I would use the spellbreaker.