m trying to think...I know Leon can kill from three, but can he kill from two as well?
Well, from Leon you have certain stage specific stuff that can even equate to instant kills.
The beauty of DOA2 Hayabusa was that his HiC Izuna would net half-life anywhere on the map, which applied to his hold variants as well. Matching it up to things like cliffs only boosted it from there. Keep in mind that the izunas were not expert holds back then, meaning you didn't have to guess between a high/low kick or punch which reduces your chance of success, as you do now.
So basically, we could hold you twice at any point in time and kill you.